A cluster of salivirus A1 (Picornaviridae) infections in newborn babies with acute gastroenteritis in a neonatal hospital unit in Hungary
| Autor: | Éva Károly, Margit Raáb, Ákos Boros, Andrea Kátai, Adrienn Karai, Gábor Reuter, Nóra Bolba, Péter Pankovics |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty 030106 microbiology Genome Viral Picornaviridae Biology Disease cluster Disease Outbreaks 03 medical and health sciences Medical microbiology Virology medicine Humans Phylogeny Retrospective Studies Hungary Molecular Epidemiology Picornaviridae Infections Public health Infant Newborn Outbreak Retrospective cohort study General Medicine Gastroenteritis Diarrhea Nurseries Hospital 030104 developmental biology Acute Disease Vomiting Etiology Nucleic Acid Conformation RNA Viral medicine.symptom |
| Zdroj: | Archives of Virology. 161:1671-1677 |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | Salivirus (family Picornaviridae) may be associated with acute gastroenteritis in humans, but there have been no reports of salivirus outbreaks. Salivirus A1 infection with faecal virus concentrations of 2.1-2.6 × 10(9)/g were identified retrospectively in newborn babies, between the ages of 1.5 and 5 days, with apparent clinical symptoms of diarrhea (100 %), fever (40 %), vomiting (40 %), and loss of appetite (40 %) in a neonatal hospital unit in Hungary in July 2013. The complete genome sequence of the salivirus (including the 5'-terminal end) was determined. Salivirus mono-infection may be associated with gastroenteritis in babies who are a few days old. Salivirus testing should be done in public health laboratories in gastroenteritis outbreaks with unknown etiology. |
| Databáze: | OpenAIRE |
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