Quantification of fracture healing with three-dimensional computed tomography
| Autor: | F. C. Bakker, H. J. T. M. Haarman, F. C. den Boer, A. J. Feilzer, R. H. Barentsen, J. A. M. Bramer, Peter Patka, E.S.M. de Klerk-de Lange |
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| Přispěvatelé: | Other departments |
| Jazyk: | angličtina |
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Bone density Computed tomography Bone healing Sensitivity and Specificity Animal model Bone Density medicine Animals Orthopedics and Sports Medicine Tibial fracture Bony Callus Fracture Healing Analysis of Variance medicine.diagnostic_test business.industry Goats fungi food and beverages General Medicine musculoskeletal system Surgery Biomechanical Phenomena Radiographic Image Enhancement Tibial Fractures body regions Casts Surgical Disease Models Animal surgical procedures operative Callus Fracture (geology) Regression Analysis Female Tomography business Tomography X-Ray Computed Biomedical engineering |
| Zdroj: | Archives of orthopaedic and trauma surgery, 117(6-7), 345-350. J.F. Bergmann |
| ISSN: | 0936-8051 |
| DOI: | 10.1007/s004020050263 |
| Popis: | Quantitative methods are necessary for an objective evaluation of fracture healing. Three-dimensional computed tomography (CT) for the measurement of callus volume and density could be such a method and was investigated in an animal model. In 23 goats a closed tibial fracture was created and stabilized with a cast. The animals were killed at 2, 4 and 6 weeks for radiographical, CT and biomechanical analysis. From the CT scans a three-dimensional reconstruction of the callus was made to measure its volume and mean density. At 2 weeks the callus volume had already reached its maximum. In contrast, callus density, torsional strength and torsional stiffness increased over time (P < 0.0001, analysis of variance, ANOVA). Multiple regression analysis showed that the callus volume was not related to the torsional properties. However, callus density was a significant explanatory variable for both torsional strength (R2 = 0.72, P < 0.0001) and torsional stiffness (R2 = 0.82, P < 0.0001). Therefore, callus density as measured by three-dimensional CT is a predictor of the extent of fracture consolidation. CT with three-dimensional reconstruction of the callus seems a valid technique for the quantification of fracture healing. |
| Databáze: | OpenAIRE |
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