Update on systemic vasculitides

Autor: Siddiq Anwar, M Yousuf Karim
Rok vydání: 2017
Předmět:
medicine.medical_specialty
Consensus
Complement Pathway
Alternative

Anti-Inflammatory Agents
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Antibodies
Monoclonal
Humanized

Antibodies
Antineutrophil Cytoplasmic

Pathology and Forensic Medicine
Biological Factors
03 medical and health sciences
0302 clinical medicine
B-Cell Activating Factor
medicine
Humans
030212 general & internal medicine
Precision Medicine
Intensive care medicine
Receptor
Anaphylatoxin C5a

Receptors
Scavenger

030203 arthritis & rheumatology
business.industry
Systemic Vasculitis
Autoantibody
Immunoglobulins
Intravenous

Lysosome-Associated Membrane Glycoproteins
General Medicine
medicine.disease
Immunoglobulin G
Immunology
Tumor Necrosis Factor Inhibitors
Interleukin-5
Rituximab
business
Vasculitis
Immunosuppressive Agents
Systemic vasculitis
Zdroj: Journal of Clinical Pathology. 70:476-482
ISSN: 1472-4146
0021-9746
DOI: 10.1136/jclinpath-2016-203875
Popis: Management of systemic vasculitis has been revolutionised over the last decade with the introduction of targeted biological agents. With an increase in both the prevalence and the recognition of vasculitis as well as the high cost of these agents, it is important to ensure their most optimal utilisation. The goals of vasculitis therapy include the induction and maintenance of remissions, preventing relapses, reducing the toxicity of therapy with the aim of reducing morbidity and mortality as well as improving the quality of life of those afflicted. This review focuses on the recent advances in the diagnosis, surveillance and treatment of these conditions.
Databáze: OpenAIRE