Vitamin B12 in Obese Adolescents with Clinical Features of Insulin Resistance

Autor:	Christopher T. Cowell, Mandy Ho, Teresa Marzulli, Megan L. Gow, Louise A. Baur, Jocelyn Halim, Nouhad El-Haddad, Sarah P. Garnett
Rok vydání:	2014
Předmět:	Blood Glucose Male obesity Pediatric Obesity medicine.medical_specialty Adolescent medicine.medical_treatment Nutritional Status lcsh:TX341-641 Cobalamin Body Mass Index Prediabetic State chemistry.chemical_compound Insulin resistance Risk Factors insulin resistance Internal medicine medicine Humans Insulin adolescents Vitamin B12 vitamin B12 deficiency cobalamin Child Randomized Controlled Trials as Topic Immunoassay Nutrition and Dietetics business.industry Communication nutritional and metabolic diseases Insulin sensitivity Vitamin B 12 Deficiency medicine.disease Obesity Metformin Vitamin B 12 Nutrition Assessment Endocrinology chemistry Female New South Wales business lcsh:Nutrition. Foods and food supply Body mass index Biomarkers Food Science medicine.drug
Zdroj:	Nutrients Nutrients, Vol 6, Iss 12, Pp 5611-5618 (2014)
ISSN:	2072-6643
Popis:	Emerging evidence indicates an association between obesity, metformin use and reduced vitamin B12 status, which can have serious hematologic, neurologic and psychiatric consequences. This study aimed to examine B12 status in obese adolescents with pre-diabetes and/or clinical features of insulin resistance. Serum B12 was measured using chemiluminescence immunoassay in 103 (43 male, 60 female) obese (mean body mass index (BMI) z-score ± SD (2.36 ± 0.29)), adolescents aged 10 to 17 years, median (range) insulin sensitivity index of 1.27 (0.27 to 3.38) and 13.6% had pre-diabetes. Low B12 (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05ff76544c4d714f30cca802b01e738 https://doi.org/10.3390/nu6125611 Zobrazit plný text záznamu