Lowering of Serum Cholesterol by the Administration of a Plant Sterol
| Autor: | Joan D. Wathen, Charles H. Duncan, Maurice M. Best, E.J. Van Loon |
|---|---|
| Rok vydání: | 1954 |
| Předmět: |
medicine.medical_specialty
Gastrointestinal tract business.industry Cholesterol Phytosterols Absorption (skin) Plant sterol chemistry.chemical_compound Blood Endocrinology Blood serum Blood chemistry chemistry Physiology (medical) Internal medicine polycyclic compounds medicine Humans Steroids lipids (amino acids peptides and proteins) Cardiology and Cardiovascular Medicine business Adverse effect Serum cholesterol |
| Zdroj: | Circulation. 10:201-206 |
| ISSN: | 1524-4539 0009-7322 |
| Popis: | The plant sterol, beta-sitosterol, has been administered to nine subjects on unrestricted diet. A sustained reduction of serum total cholesterol and a lowering of the ratio of cholesterol to lipid phosphorus occurred. Interference by sitosterol with the absorption of cholesterol, both dietary and that excreted into the gastrointestinal tract, is presumably responsible for this hypocholesterolemic effect. No toxic or undesirable side effects were observed. A means of studying the effects of a sustained lowering of serum cholesterol on atherosclerotic states would now seem to be available. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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