Predictors of (non-) response in depressed outpatients treated with a three-phase sequential medication strategy
| Autor: | P.M.J. Haffmans, H. J. Duivenvoorden, Erik Hoencamp, W.A. Dijken, H. Knegtering |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Monoamine Oxidase Inhibitors Personality Inventory media_common.quotation_subject Lithium Personality Assessment Drug Administration Schedule Psychiatric history Double-Blind Method Piperidines medicine Humans Diagnostic data Personality Depression (differential diagnoses) media_common Depressive Disorder Cross-Over Studies Hamilton Rating Scale for Depression Middle Aged medicine.disease Predictive value Sequential treatment Antidepressive Agents Psychiatry and Mental health Clinical Psychology Treatment Outcome Maprotiline Drug Therapy Combination Female Psychology Somatization Follow-Up Studies Clinical psychology |
| Zdroj: | Journal of Affective Disorders. 31:235-246 |
| ISSN: | 0165-0327 |
| DOI: | 10.1016/0165-0327(94)90099-x |
| Popis: | The predictive value of eight domains or sets of variables including sociodemographic aspects, premorbid history, symptomatology, personality, social and diagnostic data are evaluated in depressed outpatients with a Hamilton Rating Scale for Depression (HRSD) score of at least 14. Patients were treated using a three-phase sequential treatment strategy. Of the 119 patients, 88 completed the trial. The HRSD-score at the end of phases I, II or III was used as an outcome measure. Patients with an initially high HRSD-score and an obsessive-compulsive personality had a greater chance of recovery, while patients with somatization and a passive-aggressive personality had less of a chance of recovery. Variables involving psychiatric history, premorbid history or symptomatology of the depression, were not significantly related to outcome. The endogenous/non-endogenous distinction was not a predictor of response. |
| Databáze: | OpenAIRE |
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