Neonatal hemochromatosis associated with maternal autoantibodies against Ro/SS-A and La/SS-B ribonucleoproteins
| Autor: | M A Greco, B J Zitelli, Jill P. Buyon, A S Knisely, J Schoenlebe, Daniel Friedman |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Autoantigens Liver disease Fatal Outcome Pregnancy RNA Small Cytoplasmic Neonatal hemochromatosis Medicine Humans Neonatal lupus erythematosus Hemochromatosis Fetus business.industry Antemortem Diagnosis Autoantibody Infant Newborn medicine.disease Pregnancy Complications Sjogren's Syndrome Ribonucleoproteins Antibodies Antinuclear Pediatrics Perinatology and Child Health Immunology Female business Anti-SSA/Ro autoantibodies |
| Zdroj: | American journal of diseases of children (1960). 147(10) |
| ISSN: | 0002-922X |
| Popis: | • Liver disease in the fetus and neonate may be associated with maternal Sjogren's syndrome (neonatal lupus erythematosus). The infant of a mother with Sjogren's syndrome and high anti-Ro/SS-A and anti-La/SS-B antibody titers presented at 2½ weeks of age with overwhelming hepatic insufficiency and died at 6 weeks of age. Autopsy confirmed the antemortem diagnosis of neonatal hemochromatosis. We discuss the possibility of a relationship between these two conditions. (AJDC. 1993;147:1072-1075) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|