The Short-Term Effect of Weight Loss Surgery on Volumetric Breast Density and Fibroglandular Volume

Autor: Olga Schuth, Paul Vos, Dylan Suttle, Timothy L. Fitzgerald, Nasreen A. Vohra, Kathryn M. Verbanac, Swapnil D. Kachare, Bruce F. Schroeder, Jan H. Wong
Rok vydání: 2016
Předmět:
Zdroj: Obesity Surgery
ISSN: 1708-0428
0960-8923
Popis: Purpose Obesity and breast density are both associated with an increased risk of breast cancer and are potentially modifiable. Weight loss surgery (WLS) causes a significant reduction in the amount of body fat and a decrease in breast cancer risk. The effect of WLS on breast density and its components has not been documented. Here, we analyze the impact of WLS on volumetric breast density (VBD) and on each of its components (fibroglandular volume and breast volume) by using three-dimensional methods. Materials and Methods Fibroglandular volume, breast volume, and their ratio, the VBD, were calculated from mammograms before and after WLS by using Volpara™ automated software. Results For the 80 women included, average body mass index decreased from 46.0 ± 7.22 to 33.7 ± 7.06 kg/m2. Mammograms were performed on average 11.6 ± 9.4 months before and 10.1 ± 7 months after WLS. There was a significant reduction in average breast volume (39.4 % decrease) and average fibroglandular volume (15.5 % decrease), and thus, the average VBD increased from 5.15 to 7.87 % (p
Databáze: OpenAIRE