Association with meteo-climatological factors and daily emergency visits for renal colic and urinary calculi in Cuneo, Italy. A retrospective observational study, 2007–2010
| Autor: | Elena Dozio, Massimiliano Marco Corsi Romanelli, Umberto Solimene, Vincenzo Condemi, Massimo Gestro, Bruno Tartaglino, Roberto Meco |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Risk Atmospheric Science Pediatrics medicine.medical_specialty Adolescent Rain Health Toxicology and Mutagenesis Young Adult medicine Humans Renal colic Young adult Child Renal Colic Aged Retrospective Studies Ecology business.industry Incidence (epidemiology) Infant Newborn Temperature Infant Humidity Retrospective cohort study Regression analysis Emergency department Middle Aged medicine.disease Confidence interval Italy Child Preschool Female Urinary Calculi Kidney stones medicine.symptom Emergency Service Hospital business |
| Zdroj: | International Journal of Biometeorology. 59:249-263 |
| ISSN: | 1432-1254 0020-7128 |
| Popis: | The incidence of nephrolithiasis is rising worldwide, especially in women and with increasing age. Incidence and prevalence of kidney stones are affected by genetic, nutritional, and environmental factors. The aim of this study is to investigate the link between various meteorological factors (independent variables) and the daily number of visits to the Emergency Department (ED of the S. Croce and Carle Hospital of Cuneo for renal colic (RC) and urinary stones (UC) as the dependent variable over the years 2007-2010.The Poisson generalized regression models (PGAMs) have been used in different progressive ways. The results of PGAMs (stage 1) adjusted for seasonal and calendar factors confirmed a significant correlation (p 0.03) with the thermal parameter. Evaluation of the dose-response effect [PGAMs combined with distributed lags nonlinear models (DLNMs)-stage 2], expressed in terms of relative risk (RR) and cumulative relative risk (RRC), indicated a relative significant effect up to 15 lag days of lag (RR 1), with a first peak after 5 days (lag ranges 0-1, 0-3, and 0-5) and a second weak peak observed along the 5-15 lag range days. The estimated RR for females was significant, mainly in the second and fourth age group considered (19-44 and65 years): RR for total ED visits 1.27, confidence interval (CI) 1.11-1.46 (lag 0-5 days); RR 1.42, CI 1.01-2.01 (lag 0-10 days); and RR 1.35, CI 1.09-1.68 (lag 0-15 days). The research also indicated a moderate involvement of the thermal factor in the onset of RC caused by UC, exclusively in the female sex. Further studies will be necessary to confirm these results. |
| Databáze: | OpenAIRE |
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