Eosinophilic esophagitis after esophageal atresia: is there an association? Case presentation and literature review
| Autor: | C. M. Frank Kneepkens, Ramon R. Gorter, J. Patrick van der Voorn, Hugo A. Heij |
|---|---|
| Přispěvatelé: | Pediatrics, Pathology, Pediatric surgery, ICaR - Circulation and metabolism |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Eotaxin
Male Anal Canal Fundoplication Disease Kidney Gastroenterology Pathogenesis Postoperative Complications Eosinophilia Esophagitis Child Forkhead Transcription Factors General Medicine Dysphagia Combined Modality Therapy Trachea Chemokines CC Gastroesophageal Reflux Female Disease Susceptibility medicine.symptom Food Hypersensitivity Tracheoesophageal Fistula Heart Defects Congenital medicine.medical_specialty Limb Deformities Congenital Barrett Esophagus Esophagus Th2 Cells Internal medicine medicine otorhinolaryngologic diseases Humans Abnormalities Multiple Eosinophilic esophagitis Esophageal Atresia business.industry Chemokine CCL26 Infant Newborn medicine.disease Anti-Ulcer Agents Spine Hernia Hiatal Atresia Pediatrics Perinatology and Child Health Etiology Surgery business Deglutition Disorders Gene Deletion Follow-Up Studies |
| Zdroj: | Gorter, R R, Heij, H A, van der Voorn, J P & Kneepkens, C M F 2012, ' Eosinophilic esophagitis after esophageal atresia: is there an association? Case presentation and literature review ', Journal of Pediatric Surgery, vol. 47, no. 6, pp. E9-E13 . https://doi.org/10.1016/j.jpedsurg.2012.01.079 Journal of Pediatric Surgery, 47(6), E9-E13. W.B. Saunders Ltd |
| ISSN: | 0022-3468 |
| DOI: | 10.1016/j.jpedsurg.2012.01.079 |
| Popis: | Eosinophilic esophagitis (EoE) is a relatively new condition resulting in dysphagia or symptoms resembling gastroesophageal reflux disease, symptoms that also are common in patients with a history of esophageal atresia. We present 2 patients with persistent dysphagia after repair of esophageal atresia that was caused by EoE. Although the exact etiology and pathogenesis of EoE remain unclear, it is now generally accepted that it is the result of a T-helper cell 2-type immune response with a crucial role for the eosinophil-specific chemotaxis factor eotaxin 3 and eosinophils. Because there are genetic similarities between esophageal atresia and EoE, we speculate that patients with esophageal atresia are at increased risk for developing EoE. (C) 2012 Elsevier Inc. All rights reserved |
| Databáze: | OpenAIRE |
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