Post-influenza aspergillosis, do not underestimate influenza B
| Autor: | Marijke Reynders, Marc Bourgeois, E. Nulens |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
ARDS Myocarditis Fulminant 030106 microbiology Review Aspergillosis medicine.disease_cause law.invention 03 medical and health sciences law antiviral therapy medicine Pharmacology (medical) Medical history influenza B post-influenza aspergillosis Pharmacology Respiratory distress business.industry invasive pulmonary aspergillosis virus diseases medicine.disease Intensive care unit Infectious Diseases Superinfection Immunology rhabdomyolysis business |
| Zdroj: | Infection and Drug Resistance |
| ISSN: | 1178-6973 |
| Popis: | Our objective is to highlight and focus on post-influenza aspergillosis, triggered by influenza B virus. This relatively new clinical entity is often associated with a fulminant course of respiratory decline and high mortality. A 51-year immunocompetent woman, without any medical history or risk factors for developing a complicated influenza infection, was admitted to the intensive care unit. During admission, she presented with an afebrile flu-like syndrome, myocarditis, rhabdomyolysis, multiple organ failure, and evolved to severe respiratory distress. The broncho-alveolar lavage contained influenza B RNA, and the culture revealed Aspergillus fumigatus. Despite maximal organ support, immunoglobulin, antiviral and antifungal therapy, the patient died. This case demonstrates that influenza B virus may be life threatening even to immunocompetent adults and may trigger an invasive Aspergillus superinfection. |
| Databáze: | OpenAIRE |
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