Maximizing Chromatographic Information from Environmental Extracts by GCxGC-ToF-MS
| Autor: | Ewa Skoczyńska, Jacob de Boer, Peter Korytár |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Geologic Sediments
separation Analyte Resolution (mass spectrometry) Fractionation Toxicology Gas Chromatography-Mass Spectrometry Environmental Chemistry samples Toxicologie polycyclic aromatic-hydrocarbons Persistent organic pollutant Chromatography Chemistry sediments Extraction (chemistry) oil-spill analytical tool General Chemistry Wageningen Marine Research 2-dimensional gas-chromatography flight mass-spectrometry diesel fuel Comprehensive two-dimensional gas chromatography Environmental chemistry identification Environmental Pollutants Gas chromatography Time-of-flight mass spectrometry |
| Zdroj: | Environmental Science and Technology, 42(17), 6611-6618 Environmental Science and Technology 42 (2008) 17 |
| ISSN: | 1520-5851 0013-936X |
| DOI: | 10.1021/es703229t |
| Popis: | Comprehensive two-dimensional gas chromatography (GCxGC) coupled with a time-of-flight (ToF) detector allows the separation of many constituents of previously unresolved complex mixtures (UCM) of contaminants in sediment samples. In addition to the powerful chromatographic resolution, automated mass spectral deconvolution and identification system software enables a spectral deconvolution of closely eluting peaks. An extract of highly polluted sediment from the river Elbe (Czech Republic) was submitted to noninvasive extraction and fractionation, and analyzed by GCxGC-ToF-MS. More than 400 compounds were tentatively identified from three fractions. Some of the identified analytes, although not belonging to the group of priority pollutants, are known to have a toxic potential. Examples are chlorinated polycyclic aromatic hydrocarbons (PAHs), alkylated PAHs, quinones, amino-quinones, dinaphthofurans, and thiaarenes. Due to the lack of a more thorough cleanup, the life-span of the GC-column is substantially reduced, whereas the ion source of the MS needs more frequent maintenance. The procedure described is, however, not meant for routine purposes. This procedure delivers, in one run, a wealth of information that may be useful for further elucidation of toxicological properties of sediment samples by a tentative identification of previously unknown compounds. |
| Databáze: | OpenAIRE |
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