Tumor-suppressive microRNA-449a induces growth arrest and senescence by targeting E2F3 in human lung cancer cells
| Autor: | Shipeng Feng, Guoxin Wang, Xiaoshuai Ren, Xiu-Qun Yang, Ying-Jun Luo, Menghui Yin, Biliang Zhang, Zhe Wang, Pei-Zhou Liang, Xin Zhang, Jianxing He |
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| Rok vydání: | 2013 |
| Předmět: |
Oncology
Senescence Male Cancer Research medicine.medical_specialty Cell cycle checkpoint Lung Neoplasms Carcinogenesis Cell Mice Nude Cell Growth Processes medicine.disease_cause Transfection Mice Cancer stem cell In vivo Internal medicine Cell Line Tumor microRNA medicine Animals Humans Genes Tumor Suppressor RNA Small Interfering Lung cancer Cellular Senescence Mice Inbred BALB C business.industry Cell Cycle Checkpoints respiratory system Middle Aged medicine.disease respiratory tract diseases MicroRNAs medicine.anatomical_structure E2F3 Transcription Factor Cancer research Female business |
| Zdroj: | Cancer letters. 344(2) |
| ISSN: | 1872-7980 |
| Popis: | MicroRNA-449a (miR-449a) was significantly downregulated in 156 lung cancer tissues (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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