Successful Treatment of Rhinocerebral Mucormycosis with Liposomal Amphotericin B and Surgery in Two Diabetic Patients with Renal Dysfunction
| Autor: | D. Kyrmizakis, J.G. Panagiotides, J. Bizakis, Achilleas Gikas, S. Karabekios, Diamantis P. Kofteridis, Z. Saridaki |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Antifungal Agents Risk Assessment Amphotericin B Diabetes mellitus Orbital Diseases Paranasal Sinus Diseases medicine Humans Mucormycosis Pharmacology (medical) Mycosis Aged Pharmacology business.industry Acute kidney injury Acute Kidney Injury medicine.disease Combined Modality Therapy Magnetic Resonance Imaging Surgery Treatment Outcome Infectious Diseases Debridement Diabetes Mellitus Type 2 Oncology Tomography X-Ray Computed business Complication Follow-Up Studies medicine.drug Kidney disease Rare disease |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1973-9478 1120-009X |
| DOI: | 10.1179/joc.2003.15.3.282 |
| Popis: | The zygomycetes are a class of fungi that can cause a variety of infections in humans. Rhinocerebral mucormycosis is a rare disease and usually affects diabetic or immunosuppressed patients. The disease progresses rapidly and is usually fatal despite aggressive surgical and medical therapy. We report the management of two cases of rhino-sinusal and orbital mucormycosis in diabetic patients on treatment with corticosteroids, and mild renal impairment, successfully treated with a combination of aggressive surgical debridement and liposomal amphotericin B. |
| Databáze: | OpenAIRE |
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