Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep

Autor:	Ted Smith, Andrew C. Povey, Mike Mackness, Paul N. Durrington, Nicola Cherry, Stuart Thomson, Martin Dippnall, Bharti Mackness
Rok vydání:	2003
Předmět:	Male medicine.medical_specialty Insecticides Diazinon Organophosphate poisoning Paraoxon Toxicology chemistry.chemical_compound Organophosphate Poisoning Organophosphorus Compounds Gene Frequency Liver Function Tests Risk Factors Internal medicine Genetics medicine Animals Humans Genetic Predisposition to Disease General Pharmacology Toxicology and Pharmaceutics Phenylacetates Sheep dip Polymorphism Genetic Sheep biology business.industry Aryldialkylphosphatase Organophosphate Paraoxonase Esterases Middle Aged medicine.disease PON1 Occupational Diseases Endocrinology chemistry Liver Case-Control Studies biology.protein Female business Biomarkers medicine.drug
Zdroj:	Pharmacogenetics. 13(2)
ISSN:	0960-314X
Popis:	OBJECTIVES Human serum paraoxonase (PON1) hydrolyses organophosphate pesticides (OPs) entering the blood circulation and tissue fluid thus limiting toxicity. The PON1 coding region has two polymorphisms involving the amino acids at position 55 (Lt
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02f31fc51596b6482cb5abbbe78ac15 https://pubmed.ncbi.nlm.nih.gov/12563177 Zobrazit plný text záznamu