Characterization of sulfhydryl heterogeneity in human serum albumin and recombinant human serum albumin for clinical use
| Autor: | Tadashi Yasuhara, Kiyoshi Nokihara, Kazuo Ikegaya |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Serum albumin
Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry law.invention law medicine Humans Disulfides Sulfhydryl Compounds Bovine serum albumin Molecular Biology Serum Albumin Plasma serum biology Chemistry Organic Chemistry Albumin General Medicine Human serum albumin Recombinant Proteins Molecular Weight biology.protein Recombinant DNA Biotechnology medicine.drug |
| Zdroj: | Bioscience, biotechnology, and biochemistry. 74(11) |
| ISSN: | 1347-6947 |
| Popis: | Since human serum albumin has one sulfhydryl group and 17 disulfides, reactive sulfhydryl groups give rise to heterogeneity. The present paper presents a comparison of sulfhydryl heterogeneity in human serum albumin and recombinant human serum albumin for clinical use. Low molecular weight sulfhydryl compounds were identified from both sources. The recombinant albumin had a much higher sulfhydryl content than plasma serum albumin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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