Survival in Middle Ear Malignancy: A Population-Based Analysis Based on the SEER Database

Autor: Laith Mukdad, Sara Ahsan, Jose E. Alonso, Usman Alam, Marilene B. Wang, Albert Y Han, Syed F. Ahsan, Iram Shafqat
Rok vydání: 2021
Předmět:
Zdroj: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 165(1)
ISSN: 1097-6817
Popis: The purpose of this study was to investigate the clinical features and survival outcomes of patients with middle ear malignancies at a population level.Retrospective cohort study with data from a national database.National database of middle ear malignancy.Records of patients diagnosed with a middle ear malignancy from 1973 to 2016 were extracted from the SEER database (Surveillance, Epidemiology, and End Results). SPSS (version 27; IBM) was used to conduct 5-year survival analysis.The average survival for all 431 patients was 61.4 months. Five-year disease-specific survival for squamous cell carcinoma (SCCA), adenocarcinoma, other carcinoma, and noncarcinoma subtypes varied significantly at 54.6%, 82.1%, 71.8%, and 82.6%, respectively (Prognosis and treatment outcomes for primary middle ear malignancies depend on histologic subtype and age at diagnosis. The noncarcinoma and adenocarcinoma subtypes carry the best prognoses. Patients with adenocarcinoma were most likely to benefit from surgery.
Databáze: OpenAIRE