The tarsal plate manifestation of IgG4-related disease
| Autor: | Jennifer S N Verhoekx, J. A. M. van Laar, Dion Paridaens, Robert M. Verdijk, A. F. Karim |
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| Přispěvatelé: | Internal Medicine, Immunology, Pathology |
| Rok vydání: | 2019 |
| Předmět: |
Pathology
medicine.medical_specialty Tarsus (eyelids) Administration Topical Biopsy 03 medical and health sciences 0302 clinical medicine Prednisone parasitic diseases medicine Humans Pathological Glucocorticoids Fluorodeoxyglucose integumentary system medicine.diagnostic_test business.industry Neurocutaneous Syndromes fungi Eyelids Histology Middle Aged medicine.disease Mucus body regions Ophthalmology medicine.anatomical_structure Positron emission tomography 030221 ophthalmology & optometry IgG4-related disease Female sense organs Immunoglobulin G4-Related Disease business Pigmentation Disorders 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | International Ophthalmology, 39(7), 1613-1615. Springer Netherlands |
| ISSN: | 1573-2630 0165-5701 |
| Popis: | To describe a clinical case of bilateral biopsy-proven IgG4-related disease confined to the tarsal plate. Interventional case report. A 58-year-old woman presented with a tarsal swelling in the lateral part of the upper eyelids, with focal ulceration and mucus. Histology revealed fibrotic inflammation with increased IgG4-positive plasma cells fulfilling the criteria of IgG4-related disease (IgG4-RD). Serum IgG4 levels were increased, and pathological fluorodeoxyglucose uptake at positron emission tomography/CT scanning was restricted to the upper eyelids. After treatment with oral and topical prednisone, the tarsal lesions markedly regressed. Periorbital IgG4-RD may be confined to the tarsal plate. Treatment with systemic and topical steroids may induce significant regression. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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