Clinico-radiological approach to cerebral hemiatrophy

Autor: Hsiang Rong Clement Yong, Ai Peng Tan, Bingyuan Jeremy Lin, Kshitij Mankad, Yen Ling Jocelyn Wong
Rok vydání: 2018
Předmět:
Zdroj: Child's Nervous System. 34:2377-2390
ISSN: 1433-0350
0256-7040
DOI: 10.1007/s00381-018-3934-3
Popis: Cerebral hemiatrophy is an uncommon neuroimaging finding of diverse etiologies, conventionally classified into two broad categories: congenital and acquired. The authors propose an alternative pragmatic clinical approach to cerebral hemiatrophy, classifying its diverse etiologies into a single event insult such as an in utero stroke, or a progressive disorder from an inflammatory or neoplastic process, the latter of which needs urgent intervention and will be the focus of our review paper. Illustrative cases will also be presented to facilitate the understanding of the discussed disorders. A systematic approach, linking both clinical and neuroimaging features, is important to facilitate the diagnostic workup of cerebral hemiatrophy. This may potentially help avoid large-scale investigations. Determining the underlying aetiology of cerebral hemiatrophy may impact treatment and prognostication as some conditions such as Rasmussen encephalitis and Parry-Romberg syndrome may benefit from timely implementation of immunomodulatory therapy.
Databáze: OpenAIRE