| Autor: |
Yanfang Han, Mingying Shi, Xueling Mi, Sanzhong Luo |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Chemistry (Weinheim an der Bergstrasse, Germany). |
| ISSN: |
1521-3765 |
| Popis: |
Highly enantioselective α-arylation of simple ketones has been achieved by chiral primary amine catalyzed asymmetric retro-Claisen cleavage of β-diketones. This mild organocatalytic strategy enables the construction of α-aryl tertiary carbon stereocenters in good yields and excellent enantioselectivities (up to 98 % ee) with the para-quinone monoimines as aryl sources. Furthermore, oxidative catalytic asymmetric α-arylation has also been realized with free p-aminophenols. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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