Relationship between cognitive functioning, mood, and other patient factors on quality of life in metastatic brain cancer
| Autor: | Meredith Gammon, Emily N. Hayward, Gabrielle Willhelm, Helen Bae, Kristen L. Triebel, Zachary Tucker, Dario A Marotta, Matthew Mason, Adam Gerstenecker |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Emotions Experimental and Cognitive Psychology Disease Verbal learning 03 medical and health sciences Social support 0302 clinical medicine Quality of life (healthcare) Cognition Surveys and Questionnaires Humans 030212 general & internal medicine Cognitive skill Brain Neoplasms Social Support Middle Aged Psychiatry and Mental health Affect Mood Oncology 030220 oncology & carcinogenesis Quality of Life Female Psychology Neurocognitive Clinical psychology |
| Zdroj: | Psycho-oncologyREFERENCES. 29(7) |
| ISSN: | 1099-1611 |
| Popis: | Objective Neurocognitive functioning (NCF), mood disturbances, physical functioning, and social support all share a relationship with health-related quality of life (HRQOL). However, investigations into these relationships have not been conducted in persons with brain metastases (BM). Patients and methods Ninety-three newly diagnosed persons with BM were administered various cognitive batteries. Data were collected across a wide range of categories (ie, cognitive, demographic, disease/treatment, mood, social support, physical functioning). The Functional Assessment of Cancer Treatment (FACT) scale was used to measure HRQOL. Results Mood and physical function correlated with lower HRQOL in every measured domain. Verbal learning and memory correlated with every FACT subscale except emotional quality of life. Social support also correlated with several HRQOL domains. Stepwise linear regression revealed that mood predicted general well-being and several FACT subscales, including physical, emotional and cognitive well-being. Social support and physical health were predictive of general well-being. Verbal learning and memory predicted cognitive well-being. Conclusion HRQOL is a complex construct affected by numerous variables. In particular, mood, physical functioning, and learning and memory were important predictors of HRQOL, and clinicians are encouraged to obtain information in these areas during baseline assessments in persons with BM. |
| Databáze: | OpenAIRE |
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