Pertussis seroprevalence among adults of reproductive age (20–39 years) in fourteen European countries

Autor: Waldemar Rastawicki, H. O. Hallander, Kris Huygen, Julie Haider, Arno Hänninen, Evi Petridou, Sabrina Bacci, Clara M. Ausiello, Margaretha Ljungman, Fernando de Ory Manchón, Tine Dalby, Vilnele Lipnickiene, Lena Wehlin, Sharon Kühlmann-Berenzon, Tove Karin Herstad, Audun Aase, Zsuzsanna Molnár, Carla Rio, Alex-Mikael Barkoff, Qiushui He, Ilias Galanis, Odette Popovici, Denis Pierard, Maria Carollo
Přispěvatelé: Supporting clinical sciences, Microbiology and Infection Control, Clinical Biology
Rok vydání: 2021
Předmět:
Zdroj: APMIS.
ISSN: 1600-0463
0903-4641
DOI: 10.1111/apm.13165
Popis: The reported incidence of pertussis in European countries varies considerably. We aimed to study specific Bordetella pertussis seroprevalence in Europe by measuring serum IgG antibody levels to pertussis toxin (anti-PT IgG). Fourteen national laboratories participated in this study including Belgium, Denmark, Finland, Greece, Hungary, Italy, Lithuania, Malta, Norway, Poland, Portugal, Romania, Spain, and Sweden. Each country collected approximately 250 samples (N = 7903) from the age groups 20-29 years (N = 3976) and 30-39 years (N = 3927) during 2010-2013. Samples were anonymous residual sera from diagnostic laboratories and were analyzed at the national laboratories by a Swedish reference method, a commercial ELISA kit, or were sent to Sweden for analysis. The median anti-PT IgG concentrations ranged from 4 to 13.6 IU/mL. The proportion of samples with anti-PT IgG ≥100 IU/mL, indicating a recent infection ranged from 0.2% (Hungary) to 5.7% (Portugal). The highest proportion of sera with anti-PT IgG levels between 50 and
Databáze: OpenAIRE