Upper airway obstruction caused by primary lymphoplasmacytic lymphoma of the retropharyngeal space: a case report
| Autor: | Chinyere N. Asoegwu, C C Nwawolo, Okezie Obasi Kanu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population Lymphoplasmacytic Lymphoma hemic and lymphatic diseases Biopsy Case report Medicine education Lymph nodes Retropharyngeal space education.field_of_study medicine.diagnostic_test business.industry Macroglobulinemia Airway obstruction medicine.disease Lymphoma medicine.anatomical_structure Dyspnea Otorhinolaryngology RF1-547 Lymphoplasmacytic lymphoma Histopathology Radiology business Retropharyngeal space tumour |
| Zdroj: | The Egyptian Journal of Otolaryngology, Vol 37, Iss 1, Pp 1-5 (2021) |
| ISSN: | 2090-8539 1012-5574 |
| Popis: | Background Primary malignant tumours of the retropharyngeal space are rare with only a few case reports in the literature. Lymphoplasmacytic lymphoma is a rare subtype of non-Hodgkin lymphoma and is very rarely found as a primary tumour of the retropharyngeal space. Case presentation We report the case of progressive upper airway obstruction in a 49-year-old male caused by a primary malignant tumour of the retropharyngeal space lymph nodes. He had an emergency tracheostomy to relieve the upper airway obstruction followed a week later by an elective surgical excision of the tumour via the trans-cervical route. A mixed population of lymphocytes, with a marked presence of Dutcher bodies, was noted on histopathology and positive CD20 on immunohistochemistry, confirming the lymphoplasmacytic lymphoma of the retropharyngeal space. The watchful waiting treatment method for the lymphoma was employed for him since he had no symptoms relating to lymphoma and no serum Waldenström’s macroglobulinemia. He has remained symptom-free 3 years post-surgery. Conclusion Primary malignant tumours involving the retropharyngeal space lymph nodes are very rare. They can rarely grow to a size huge enough to cause obstructive upper aerodigestive symptoms. Primary lymphoma of the retropharyngeal space should be considered in the diagnosis of the tumours involving the retropharyngeal space lymph nodes. Excisional biopsy is important to obtain tissue for histopathological diagnosis and the relief of upper aerodigestive tract obstruction when present. |
| Databáze: | OpenAIRE |
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