Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system: global challenges and national solutions

Autor: Martina C. Cornel, Lidewij Henneman, Rachèl V. van Schendel, Carla G. van El, Eva Pajkrt
Přispěvatelé: APH - Quality of Care, APH - Personalized Medicine, Amsterdam Reproduction & Development (AR&D), Obstetrics and Gynaecology, Human genetics
Jazyk: angličtina
Rok vydání: 2017
Předmět:
0301 basic medicine
Health Knowledge
Attitudes
Practice
Internationality
Cost-Benefit Analysis
Down syndrome
Decision Making
Public debate
Context (language use)
Prenatal care
030105 genetics & heredity
Health informatics
Ultrasonography
Prenatal
Health administration
03 medical and health sciences
0302 clinical medicine
Nursing
Pregnancy
Prenatal Diagnosis
Health care
Humans
Medicine
Genetic Testing
Innovation
Qualitative Research
Health policy
Netherlands
030219 obstetrics & reproductive medicine
business.industry
lcsh:Public aspects of medicine
Health Policy
Stakeholder
Prenatal screening
lcsh:RA1-1270
Patient Acceptance of Health Care
Public relations
Aneuploidy
Non-invasive prenatal testing
Implementation
Female
Diffusion of Innovation
business
Qualitative analysis
Biomarkers
Research Article
Zdroj: BMC Health Services Research, Vol 17, Iss 1, Pp 1-10 (2017)
BMC health services research, 17(1). BioMed Central
Van Schendel, R V, Van El, C G, Pajkrt, E, Henneman, L & Cornel, M C 2017, ' Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system : Global challenges and national solutions ', BMC Health Services Research, vol. 17, no. 1, 670 . https://doi.org/10.1186/s12913-017-2618-0
BMC Health Services Research
BMC Health Services Research, 17(1):670. BioMed Central
ISSN: 1472-6963
DOI: 10.1186/s12913-017-2618-0
Popis: Background Since the introduction of non-invasive prenatal testing (NIPT) in 2011, mainly by commercial companies, a growing demand for NIPT from the public and healthcare professionals has been putting pressure on the healthcare systems of various countries. This study identifies the challenges of establishing a responsible implementation of NIPT for aneuploidy in prenatal healthcare, by looking at the Netherlands. Methods A mixed methods approach involving 13 stakeholder interviews, document analysis and (participatory) observations of the Dutch NIPT Consortium meetings were used. The Diffusion of Innovation Theory and a Network of Actors model were used to interpret the findings. Results Implementation of NIPT was facilitated by several factors. The set-up of a national NIPT Consortium enabled discussion and collaboration between stakeholders. Moreover, it led to the plan to offer NIPT through a nationwide research setting (TRIDENT studies), which created a learning phase for careful implementation. The Dutch legal context was perceived as a delaying factor, but eventually gave room for the parties involved to organise themselves and their practices. Conclusions This study shows that implementing advanced technologies with profound effects on prenatal care benefit from a learning phase that allows time to carefully evaluate the technical performance and women’s experiences and to enable public debate. Such a coordinated learning phase, involving all stakeholders, will stimulate the process of responsible and sustainable implementation.
Databáze: OpenAIRE
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