There are receptors for neurotensin in the caudate nucleus and posterior hypothalamus
| Autor: | Kalikhevich Vn, Klimov Pk, G. M. Barashkova, Fokina Aa, Ardemasova Za, A. F. Yakimovskii, N. F. Suvorov, M. V. Andrianova |
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| Rok vydání: | 1984 |
| Předmět: |
Male
medicine.medical_specialty Hypothalamus Posterior Period (gene) Conditioning Classical Hypothalamus Caudate nucleus Synaptic Transmission chemistry.chemical_compound Dogs Internal medicine medicine Animals Receptors Neurotensin Receptor Neurotensin Gastric Juice Dose-Response Relationship Drug General Neuroscience Posterior hypothalamus digestive oral and skin physiology Receptors Neurotransmitter Endocrinology nervous system chemistry Reflex Caudate Nucleus Salivation hormones hormone substitutes and hormone antagonists Histamine |
| Zdroj: | Neuroscience and Behavioral Physiology. 14:416-420 |
| ISSN: | 1573-899X 0097-0549 |
| Popis: | It was established in chronic experiments on dogs that the introduction of neurotensin in a dose of 3 or 10 micrograms in 1.5 microliters into the caudate nucleus changes the parameters of the conditioned and unconditioned food reflexes: a 31% shortening of the latent period and a 56% increase in the magnitude of the reflex. Microapplication of neurotensin in the same doses in the posterior region of the hypothalamus enhanced the secretory function of the gland caused by the introduction of histamine. It was concluded that the caudate nucleus and hypothalamus contain cells possessing receptors for neurotensin, which participate in mechanisms of formation of the conditioned reflex and central influence on the organs of the digestive system. |
| Databáze: | OpenAIRE |
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