| Autor: |
Antonio Rispo, Roberto de Sire, Pier Paolo Mainenti, Nicola Imperatore, Anna Testa, Simone Maurea, Simona Ricciolino, Olga Maria Nardone, Oriana Olmo, Fabiana Castiglione |
| Přispěvatelé: |
Rispo, Antonio, de Sire, Roberto, Mainenti, Pier Paolo, Imperatore, Nicola, Testa, Anna, Maurea, Simone, Ricciolino, Simona, Nardone, Olga Maria, Olmo, Oriana, Castiglione, Fabiana |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Inflammatory bowel diseases. |
| ISSN: |
1536-4844 |
| Popis: |
Background Diagnosis of Crohn’s disease (CD) requires ileo-colonoscopy (IC) and cross-sectional evaluation. Recently, “echoscopy” has been used effectively in several settings, although data about its use for CD diagnosis are still limited. Our aim was to evaluate the diagnostic accuracy of handheld bowel sonography (HHBS) in comparison with magnetic resonance enterography (MRE) for CD diagnosis. Methods From September 2019 to June 2021, we prospectively recruited consecutive subjects attending our third level IBD Unit for suspected CD. Patients underwent IC, HHBS, and MRE in random order with operators blinded about the result of the other procedures. Bivariate correlation between MRE and HHBS was calculated by Spearman coefficient (r). To test the consistency between MRE and HHBS for CD location and complications, the Cohen’s k measure was applied. Results Crohn’s disease diagnosis was made in 48 out of 85 subjects (56%). Sensitivity, specificity, positive predictive values, and negative predictive values for CD diagnosis were 87.50%, 91.89%, 93.33%, and 85% for HHBS; and 91.67%, 94.59%, 95.65%, and 89.74% for MRE, without significant differences in terms of diagnostic accuracy (89.41% for HHBS vs 92.94% for MRE, P = NS). Magnetic resonance enterography was superior to HHBS in defining CD extension (r = 0.67; P < .01) with a better diagnostic performance than HHBS for detecting location (k = 0.81; P < .01), strictures (k = 0.75; P < .01), abscesses (k = 0.68; P < .01), and fistulas (k = 0.65; P < .01). Conclusion Handheld bowel sonography and MRE are 2 accurate and noninvasive procedures for diagnosis of CD, although MRE is more sensitive in defining extension, location, and complications. Handheld bowel sonography could be used as effective ambulatory (or out-of-office) screening tool for identifying patients to refer for MRE examination due to high probability of CD diagnosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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