Nail involvement can predict enthesopathy in patients with psoriasis
| Autor: | Raquel Rivera Díaz, Pablo Luis Ortiz Romero, María Castellanos-González, Julio Sánchez, Beatriz Esther Joven, Francisco Vanaclocha-Sebastián, Eva María Andrés-Esteban |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Dermatology Comorbidity Enthesopathy Asymptomatic Risk Assessment Sensitivity and Specificity 030207 dermatology & venereal diseases 03 medical and health sciences Psoriatic arthritis Nail Diseases 0302 clinical medicine Age Distribution Risk Factors Psoriasis medicine Prevalence Humans In patient Sex Distribution Subclinical infection 030203 arthritis & rheumatology business.industry Reproducibility of Results Middle Aged medicine.disease Prognosis medicine.anatomical_structure Early Diagnosis Spain Nail (anatomy) Female medicine.symptom business |
| Zdroj: | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 14(11) |
| ISSN: | 1610-0387 |
| Popis: | SummaryBackground Although subclinical enthesopathy is a well-established diagnostic criterion for psoriatic arthritis (PsA), it is frequently overlooked, as many patients are asymptomatic. The possibility of finding a clinical clue predicting enthesopathy would help clinicians establish an early diagnosis of PsA. Material and methods A prospective single-center study of a total of 90 patients with psoriasis was conducted to assess the presence of entheseal abnormalities as detected by ultrasound, and to determine any correlation with nail involvement. Results Entheseal abnormalities were found in 23 patients (25.5 %), 19 (82.6 %) of whom showed nail involvement, whereas four (17.4 %) individuals did not. Enthesopathy was present in 31.1 % (19/61) of patients with onychopathy compared to 13.8 % (4/29) of those without nail involvement (p = 0.07). There was a significant correlation between target NAPSI score and evidence of enthesopathy. In addition, the number of nails affected also showed a significant correlation with the presence of enthesopathy (p = 0.035). Conclusions Clinical evidence of onychopathy may be the clue to an early diagnosis of enthesopathy in psoriasis patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text