Increased preoperative glucose levels are associated with perioperative mortality in patients undergoing noncardiac, nonvascular surgery
| Autor: | Frodo Schreiner, Jeroen J. Bax, Peter G. Noordzij, Martin Dunkelgrun, Miklos D. Kertai, Eric Boersma, Jan Klein, Don Poldermans, Harm H.H. Feringa |
|---|---|
| Přispěvatelé: | Anesthesiology, Cardiology, Clinical Genetics |
| Rok vydání: | 2007 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty Endpoint Determination Cardiovascular Complication Endocrinology Diabetes and Metabolism Intraoperative Period Endocrinology Risk Factors Diabetes mellitus Epidemiology Diabetes Mellitus Odds Ratio medicine Humans Prediabetes Aged Cause of death business.industry Data Collection General Medicine Odds ratio Perioperative Middle Aged medicine.disease Surgery Cardiovascular Diseases Case-Control Studies Hyperglycemia Surgical Procedures Operative Cohort Female business |
| Zdroj: | European Journal of Endocrinology, 156(1), 137-142. Bioscientifica Ltd |
| ISSN: | 1479-683X 0804-4643 |
| Popis: | Objective: To determine the relationship between preoperative glucose levels and perioperative mortality in noncardiac, nonvascular surgery. Research design and methods: We performed a case–control study in a cohort of 108 593 patients who underwent noncardiac surgery at the Erasmus MC during 1991–2001. Cases were 989 patients who underwent elective noncardiac, nonvascular surgery and died within 30 days during hospital stay. From the remaining patients, 1879 matched controls (age, sex, calendar year, and type of surgery) were selected. Information was obtained regarding the presence of cardiac risk factors, medication, and preoperative laboratory results. Preoperative random glucose levels Results: Preoperative glucose levels were available in 904 cases and 1247 controls. A cardiovascular complication was the primary cause of death in 207 (23%) cases. Prediabetes glucose levels were associated with a 1.7-fold increased mortality risk compared with normoglycemic levels (adjusted odds ratio (OR) 1.7 and 95% confidence interval (CI) 1.4–2.1; PP Conclusions: Preoperative hyperglycemia is associated with increased (cardiovascular) mortality in patients undergoing noncardiac, nonvascular surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|