Bisphenol A Accumulation in the Freshwater Clam Pisidium amnicum at Low Temperatures
| Autor: | Jussi V. K. Kukkonen, Jani O. Honkanen, Jari Heinonen, Ismo J. Holopainen |
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| Rok vydání: | 2002 |
| Předmět: |
Bisphenol A
Health Toxicology and Mutagenesis Lowest temperature recorded on Earth Biological Availability Bioconcentration Toxicology medicine.disease_cause chemistry.chemical_compound Phenols medicine Animals Ecotoxicology Toxicokinetics Tissue Distribution Estrogens Non-Steroidal Benzhydryl Compounds biology Ecology Temperature Environmental factor General Medicine biology.organism_classification Bivalvia Pollution Pisidium amnicum chemistry Environmental chemistry Water Pollutants Chemical |
| Zdroj: | Archives of Environmental Contamination and Toxicology. 43:50-55 |
| ISSN: | 1432-0703 0090-4341 |
| DOI: | 10.1007/s00244-002-1146-y |
| Popis: | Toxicokinetics of 14C-labeled bisphenol A (BPA) was studied in the small freshwater clam Pisidium amnicum at four ecologically relevant low temperatures (2, 6, 8, and 12°C). The uptake clearance (k u ) of BPA increased from 1.49 to 6.55 ml · g−1 · h−1 as temperature increased from 2 to 8°C but decreased slightly again at the highest temperature. The depuration of BPA was very slow and statistically insignificant at 2°C, but the depuration rate (k d ) increased linearly as temperature increased from 2 to 12°C. The longest half-life of BPA in clam tissues, 221 h, was found at the lowest temperature, and the highest bioconcentration factor of 144 was measured at 8°C. Data show that P. amnicum accumulates BPA so that the bioconcentration factor rises over 100 at each temperature tested. Further, the data demonstrate the importance of temperature on the processes that control both the uptake and elimination of this compound. |
| Databáze: | OpenAIRE |
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