Relative Importance of Traditional Risk Factors for Malignant Melanoma in the Czech Population
Autor: | Filip Rob, Jana Hercogová, Anna Jiráková, Lucie Rajská, Dana Gopfertova, Zuzana Sečníková, Zdeněk Šmerhovský |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty Venereology Skin Neoplasms Population Protective factor 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Epidemiology medicine Humans education Melanoma Aged Czech Republic education.field_of_study business.industry Incidence (epidemiology) Public health Incidence Public Health Environmental and Occupational Health Case-control study General Medicine Middle Aged medicine.disease Surgery 030220 oncology & carcinogenesis Case-Control Studies Female Skin cancer business |
Zdroj: | Central European journal of public health. 24(4) |
ISSN: | 1210-7778 |
Popis: | Aim: The Czech Republic is one of the leading European countries in incident cases of malignant melanoma (MM), which is on the rise. The study objective was to assess the strength of associations between MM and the known generally accepted risk factors for MM in the population of the Czech Republic. Methods: The study was designed as a case-control study where cases were incident cases of MM detected at the Department of Dermatology and Venereology of the Bulovka Hospital. Controls were selected from cancer-free patients admitted to departments other than Dermatology and Venereology. Validated questionnaires were used to collect demographic, epidemiological, and clinical data. Results: The binary logistic model shows the main risk factors for MM: male, female (OR=0.292, 95% CI=0.175-0.486), a changed mole (OR=6.371, 95% CI=3.774-10.756), a history of skin cancer (OR=95.704, 95% CI=37.241-10.756), and sunbeds use (OR=3.594, 95% CI=1.288-10.028). Using sunscreen products was considered as a protective factor against MM (OR=0.253, 95% CI=0.137-0.466). Conclusion: The primary and secondary prevention increasingly emerges as a public health priority in the effort to reverse the negative trend in cases of MM and mortality from this disease in the Czech Republic. A prerequisite for an effective secondary prevention through screening is, among others, the identification of the population groups at highest risk for MM. |
Databáze: | OpenAIRE |
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