Biochemical and behavioural effects of acute tryptophan depletion in abstinent bulimic subjects: a pilot study
| Autor: | Phil J. Cowen, A. E. S. Walsh, Christopher G. Fairburn, Paul M. Salkovskis, A.D. Oldman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Food intake media_common.quotation_subject Pilot Projects Eating Feeding behavior Internal medicine medicine Humans Bulimia Applied Psychology media_common Psychiatric Status Rating Scales Test meal Depressive Disorder Tryptophan Appetite Middle Aged Abstinence Psychiatry and Mental health Mood Endocrinology Vomiting Female medicine.symptom Psychology |
| Zdroj: | Scopus-Elsevier |
| Popis: | SYNOPSISWe studied the effect of acute tryptophan (TRP) depletion in a group of eight abstinent bulimic (BN) subjects and in 12 healthy female controls. Despite being free of episodes of bingeeating and vomiting for a prolonged period, the abstinent BN subjects still appeared to practice dietary restraint as judged by their food intake in a test meal. In addition, their plasma TRP concentrations were significantly lower than those of the controls. Administration of a TRP-free amino acid load (52 g) significantly lowered plasma total and free TRP. However, compared to a balanced amino acid load, this procedure did not have significant effects on mood, appetite or food intake in either the abstinent BN subjects or the healthy controls. |
| Databáze: | OpenAIRE |
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