Evaluation of left ventricular diastolic function in nonhypertensive nondiabetic hemodialysis patients

Autor: Ahmet Yilmaz, Zekeriya Küçükdurmaz, Recep Kurt, Hekim Karapinar, Yusuf Karavelioğlu, Mehmet Gungor Kaya, Sultan Ozkurt, Mahmut Akpek, Mikail Yarlioglues, Arif Arisoy
Přispěvatelé: [Karavelioglu, Yusuf -- Arisoy, Arif] Hitit Univ, Corum Training & Res Hosp, Dept Cardiol, TR-19001 Corum, Turkey -- [Ozkurt, Sultan] Hitit Univ, Corum Training & Res Hosp, Dept Nephrol, TR-19001 Corum, Turkey -- [Karapinar, Hekim -- Kucukdurmaz, Zekeriya -- Kurt, Recep -- Yilmaz, Ahmet] Cumhuriyet Univ, Sch Med, Dept Cardiol, Sivas, Turkey -- [Yarlioglues, Mikail -- Akpek, Mahmut -- Kaya, Mehmet G.] Erciyes Univ, Sch Med, Dept Cardiol, Kayseri, Turkey, Hitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
Rok vydání: 2013
Předmět:
Zdroj: Blood Pressure Monitoring. 18:239-246
ISSN: 1359-5237
2401-3617
Popis: WOS: 000324527900001
PubMed ID: 24013617
Aim Diastolic dysfunction (DD) is common in hemodialysis (HD) patients. Because diabetes mellitus (DM) and hypertension (HT) are also common in this patient group, the exact reason for DD in HD patients is not clear. The present study evaluated left ventricular (LV) diastolic function in HD patients without DM and HT. Methods Fifty patients on HD and 34 age-matched and sex-matched healthy control individuals were enrolled. Echocardiography was performed in all participants. LV systolic and diastolic functions were evaluated by B-mode echocardiography, pulsed wave, and tissue Doppler imaging. The HD patients were divided into two groups according to the presence or absence of left ventricular hypertrophy (LVH) in echocardiography. Results LV dimensions and systolic function were within normal limits and similar between groups. However, the HD patients had significantly worse diastolic function (E/A: 0.78 +/- 0.26 vs. 1.19 +/- 0.28, P < 0.001, e '/a ' septal: 0.77 +/- 0.36 vs. 1.04 +/- 0.21, P < 0.001) and increased filling pressure (E/e ': 8.55 +/- 3.2 vs. 5.79 +/- 1.93, P < 0.001). Thirty-one (62%) patients had LVH, whereas 19 (38%) patients did not have LVH. LV systolic and diastolic functions were similar in HD patients with and without LVH. Seventeen (55%) hypertrophies were concentric and 14 (45%) were eccentric. Diastolic functions were similar in patients with either concentric or eccentric hypertrophy. Conclusion Diastolic function is impaired in HD patients even in the absence of diseases that can cause DD such as HT and DM.
Databáze: OpenAIRE