Small changes in calcium replacement therapy triggering hypercalcaemia and rising creatinine – a case series
| Autor: | Luis Loureiro Harrison, Alison Crooks, Fiona Green, Thalakunte M Muniraju, Michael Kelly |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Hypercalcaemia Hypoparathyroidism 030232 urology & nephrology chemistry.chemical_element 030204 cardiovascular system & hematology Calcium 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Vitamin D and neurology Humans Renal Insufficiency skin and connective tissue diseases Adverse effect Creatinine business.industry Acute kidney injury General Medicine Middle Aged medicine.disease Regimen chemistry Hypercalcemia Thyroidectomy Female sense organs business |
| Zdroj: | Scottish Medical Journal. 65:32-37 |
| ISSN: | 2045-6441 0036-9330 |
| DOI: | 10.1177/0036933019877338 |
| Popis: | In this article, we present four cases of renal failure secondary to hypercalcaemia which were brought to the attention of our hospital's nephrology team. These happened in the setting of simple medication changes for hypoparathyroidism post-thyroid surgery. These cases have in common minor changes in preparations leading to significant adverse events. In two cases, excipient changes were the only changes identified in the patients' regimen. In all cases, cessation of the offending calcium preparation and treatment with IV rehydration led to a return to baseline creatinine levels. Communicating to patients the importance of consistency in how calcium and vitamin D supplements are taken is crucial in preventing adverse effects. Prescribers should be aware of excipient changes and that these are not always clinically insignificant. |
| Databáze: | OpenAIRE |
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