Giant Squamous Cell Carcinoma on Chronic Lichen Planus on the Ankle - A Case Report and Short Literature Review
| Autor: | Torello Lotti, Aleksandra Vojvodic, Uwe Wollina, Jacqueline Schönlebe, Claudia Krönert |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
lcsh:Medicine Case Report 030209 endocrinology & metabolism Malignancy Sepsis 03 medical and health sciences 0302 clinical medicine stomatognathic system Squamous cell carcinoma medicine 030212 general & internal medicine Risk factor skin and connective tissue diseases integumentary system business.industry lcsh:R Verrucous Lesion Histology General Medicine Chronic lichen planus medicine.disease Dermatology stomatognathic diseases medicine.anatomical_structure Malignant transformation Surgery Oral lichen planus Ankle Lichen planus business |
| Zdroj: | Open Access Macedonian Journal of Medical Sciences; Vol 7 No 18 (2019): Sep 30 (Global Dermatology); 3061-3063 Open Access Macedonian Journal of Medical Sciences Open Access Macedonian Journal of Medical Sciences, Vol 7 (2019) |
| ISSN: | 1857-9655 |
| DOI: | 10.3889/oamjms.2019.553 |
| Popis: | BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common malignancy of skin. Although a major risk factor is a chronic exposure to ultraviolet radiation, preexistent chronic inflammatory disorders may also possess an increased risk for SCC. That is not the case for cutaneous lichen planus in contrast to oral lichen planus and oral SCC. CASE REPORT: We report the case of an 87-year-old Caucasian woman presenting with a giant verrucous tumour on the left ankle. She suffered from long-standing disseminated lichen planus. Histology confirmed the diagnosis of SCC on partly verrucous lichen planus. The course was complicated due to sepsis. An emergency transfemoral amputation became necessary. The patients survived and could be released into her nursery. A literature review underlined the rarity of SCC on lichen planus of the skin. Most of these rare cases were in patients in their second half of life on the lower legs. Hypertrophic lichen plnaus was overrepresented. CONCLUSIONS: Although very rare by number, SCC can complicate lichen planus and lead to the life-threatening situation. Atypical verrucous lesions on lichen planus warrant a histologic analysis. Surgery is the treatment of choice for cutaneous SCC. |
| Databáze: | OpenAIRE |
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