A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate
| Autor: | Marlene R Moster, Jeffrey C Oehler, Joseph I Markoff, Neil T Choplin, Lindsay A. Nelson, Parul Ichhpujani, William C. Stewart |
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| Rok vydání: | 2012 |
| Předmět: |
genetic structures
Timolol hemihydrate Ocular hypertension Timolol Pharmacology Istalol chemistry.chemical_compound Betimol medicine Timolol maleate Potassium sorbate integumentary system business.industry Hemihydrate Glaucoma Timolol maleate with potassium sorbate medicine.disease eye diseases Comfort Ophthalmology chemistry Anesthesia Original Article sense organs Once daily business medicine.drug |
| Zdroj: | Journal of Current Glaucoma Practice |
| ISSN: | 0974-0333 |
| Popis: | Objective: To evaluate by survey the comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Design: A prospective, multicenter, observational, non-interventional study. Participants: One hundred and three patients of open-angle glaucoma or ocular hypertension who were ≥21 years old and were currently prescribed timolol hemihydrate (once or twice daily) or timolol maleate with potassium sorbate once daily as monotherapy or as a part of two-drug therapy. Materials and methods: Study was performed at seven clinical sites in the United States. Patients were surveyed on comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Results: A difference between timolol hemihydrate and timolol maleate with potassium sorbate for questions 1 (burning/stinging on instillation, p < 0.001) and 4 (tearing on instillation, p = 0.024) was noted. There were no differences between treatment groups for any other question (p > 0.05). Conclusion: This survey suggests that timolol hemihydrate is associated with less stinging/burning and tearing than timolol maleate with potassium sorbate. How to cite this article: Stewart WC, Oehler JC, Choplin NT, Markoff JI, Moster MR, Ichhpujani P, Nelson LA. A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate. J Current Glau Prac 2013;7(1):11-16. |
| Databáze: | OpenAIRE |
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