Event-related potentials in an auditory oddball situation in the rat
Autor: | Alessandro E. P. Villa, Jan Eriksson |
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Přispěvatelé: | Issartel, Jean-Paul, Laboratory of Neuroheuristics, Université de Lausanne = University of Lausanne (UNIL), Laboratory of Neurobiophysics, University Joseph-Fourier |
Rok vydání: | 2005 |
Předmět: |
Statistics and Probability
Auditory perception medicine.medical_specialty MESH: Rats Acoustics education Auditory oddball Mismatch negativity Stimulus (physiology) Audiology Auditory cortex behavioral disciplines and activities General Biochemistry Genetics and Molecular Biology MESH: Rats Long-Evans Event-related potential otorhinolaryngologic diseases medicine Animals MESH: Animals Rats Long-Evans Evoked Potentials Applied Mathematics Significant difference General Medicine Long evans Rats MESH: Evoked Potentials Auditory MESH: Evoked Potentials Modeling and Simulation Evoked Potentials Auditory Psychology psychological phenomena and processes |
Zdroj: | BioSystems BioSystems, Elsevier, 2005, 79 (1-3), pp.207-12. ⟨10.1016/j.biosystems.2004.09.017⟩ |
ISSN: | 0303-2647 |
DOI: | 10.1016/j.biosystems.2004.09.017 |
Popis: | International audience; Evoked potentials were recorded from the auditory cortex of both freely moving and anesthetized rats when deviant sounds were presented in a homogenous series of standard sounds (oddball condition). A component of the evoked response to deviant sounds, the mismatch negativity (MMN), may underlie the ability to discriminate acoustic differences, a fundamental aspect of auditory perception. Whereas most MMN studies in animals have been done using simple sounds, this study involved a more complex set of sounds (synthesized vowels). The freely moving rats had previously undergone behavioral training in which they learned to respond differentially to these sounds. Although we found little evidence in this preparation for the typical, epidurally recorded, MMN response, a significant difference between deviant and standard evoked potentials was noted for the freely moving animals in the 100-200 ms range following stimulus onset. No such difference was found in the anesthetized animals. |
Databáze: | OpenAIRE |
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