Risk factors for fracture in a UK population: a prospective cohort study

Autor: Yvonne Birks, Suezann Puffer, David J. Torgerson, Jill Porthouse, Ian Watt, Sarah Cockayne
Rok vydání: 2004
Předmět:
Zdroj: QJM : monthly journal of the Association of Physicians. 97(9)
ISSN: 1460-2725
Popis: BACKGROUND: Common clinical risk factors for fracture in older women have been identified. To date, most of these risk factors have not been confirmed in a UK population. AIM: To confirm the important risk factors for fracture in older women. DESIGN: Comprehensive cohort study (CCS) with a nested randomized controlled trial. METHODS: The CCS included 4292 women aged >70 years. We assessed potential risk factors for fracture, and followed-up participants for 24 months for incidence of non-vertebral fractures. RESULTS: Odds ratios (ORs) for predicting any non-vertebral fracture were: previous fracture, 2.67 (95%CI 2.10–3.40); a fall in the last 12 months, 2.06 (95%CI 1.63–2.59); and age (per year increase), 1.03 (95%CI 1.01–1.05). ORs for predicting hip fracture were: previous fracture, 2.31 (95%CI 1.31–4.08); low body weight (
Databáze: OpenAIRE