Are third-trimester adipokines associated with higher metabolic risk among women with gestational diabetes?
| Autor: | C. Maurice, Emmanuel Disse, M. Claret, E. Mathiotte, L. Millot, Anne Charrié, Jocelyne Drai, Charles Thivolet, O. Dupuis, D. Honnorat, Chantal Simon, E. Durand, Lionel Garnier |
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| Přispěvatelé: | Département Endocrinology et Diabétologie, Hospices Civils de Lyon (HCL), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Département Endocrinologie, Centre Hospitalier Universitaire de Saint-Etienne, Pole IMER, Unité Recherch Clinique, Départment de Biochimie, Pole IMER, Unité Recherche Clinique, Départment Gynécologie et Obstétrique, PHRC Rhone-Alpes-Auvergne, Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Leptin
endocrine system diseases Endocrinology Diabetes and Metabolism Gastroenterology Severity of Illness Index Body Mass Index Impaired glucose tolerance Cohort Studies 0302 clinical medicine Endocrinology Pregnancy Risk Factors Prenatal Diagnosis cytokine 030212 general & internal medicine Prospective Studies 2. Zero hunger syndrome métabolique Postpartum Period metabolic x syndrome General Medicine [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism gestational diabete Gestational diabetes Gestation Female Adiponectin France diabète medicine.medical_specialty Pregnancy Trimester Third dépistage Adipokine 030209 endocrinology & metabolism metabolic syndrome 03 medical and health sciences Internal medicine Internal Medicine medicine Humans adipokine business.industry screening nutritional and metabolic diseases Overweight medicine.disease Impaired fasting glucose Pregnancy Complications Diabetes Gestational Diabetes Mellitus Type 2 Metabolic syndrome Insulin Resistance business Body mass index Biomarkers |
| Zdroj: | Diabetes and Metabolism Diabetes and Metabolism, Elsevier Masson, 2015, 41 (5), pp.393-400. ⟨10.1016/j.diabet.2015.03.003⟩ |
| ISSN: | 1262-3636 |
| DOI: | 10.1016/j.diabet.2015.03.003⟩ |
| Popis: | Aim. This study aimed to determine whether third-trimester adipokines during gestational diabetes (GDM) are associated with higher metabolic risk.Methods. A total of 221 women with GDM (according to IADPSG criteria) were enrolled between 2011/11 and 2013/6 into a prospective observational study (IMAGE), and categorized as having elevated fasting blood glucose (FBG) or impaired fasting glucose (IFG, n=36) if levels were >= 92 mg/dL during a 75-g oral glucose tolerance test (OGTT), impaired glucose tolerance (IGT, n= 116) if FBG was = 92 mg/dL and 1-h or 2-h OGTT values were elevated.Results. - Pre-gestational body mass index (BMI) was higher in women with IFG or IFSG compared with JOT (P |
| Databáze: | OpenAIRE |
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