Phalangeal osteosonogrammetry age-related changes and assessment of a Lebanese reference population
| Autor: | Ziad Tannous, Marie-Helene Gannage Yared, Georges Farah, Serge Jalkh, Dany Sawan, Ghassan Maalouf, Rita-Maria Chidiac, Joseph Wehbe, Alexandre Nehme |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
medicine.medical_specialty Aging Histology Physiology Endocrinology Diabetes and Metabolism Osteoporosis Population Finger Phalanges Bone Density Reference Values Age related medicine Humans Reference population Lebanon education Aged Ultrasonography education.field_of_study business.industry Ultrasound Age Factors Anthropometry Middle Aged medicine.disease Surgery Menopause Postmenopause Female business Bone profile Demography |
| Zdroj: | Bone. 40(6) |
| ISSN: | 8756-3282 |
| Popis: | This study was aimed to assess age changes in quantitative ultrasonometry (QUS) of the phalanx in a sample of Lebanese women to determine a reference data for the Lebanese population. Velocity of ultrasound (amplitude-dependent speed of sound; AD-SOS) and the interpretation of the ultra sound signal (ultrasound bone profile index; UBPI) were measured in 211 women with a mean age of 50 years (range 20-79 years) using a DBM sonic Bone profiler device. Women were randomly selected and asked to participate in a nation-wide screening program. Age is an important factor affecting the two parameters: the AD-SOS declines from 2200 m/s at 20 years to 1700 at 80 years. The climacteric condition is another important factor, with significant decrease of the two parameters after the menopause (P0.0001). This effect is highly influenced by the duration of the postmenopausal period. No influence of weight or height was observed in UBPI variability. The AD-SOS values are similar to those of European population before the age of 50 years. After this age, a significant difference is noted between the two populations. Phalangeal QUS curve of AD-SOS and UBPI are age-dependent. The Lebanese reference curve for AD-SOS is significantly lower from the European curve after the menopause; a 2% decrease in AD-SOS after the age of 50 years can be observed. This decrease in AD-SOS reference values is relevant in the classification of osteoporotic subjects; in fact, if we had used the European reference data set, we had generated 10.9% more Lebanese patients being osteoporotic. Therefore, the use of our standardized reference data reduces the risk of overestimating osteoporosis in the Lebanese population. |
| Databáze: | OpenAIRE |
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