Plasma Vasopressin, Cortisol, and Growth Hormone Concentrations in Relation to Surgery in the Suprasellar Region

Autor: Per Soelberg Sørensen, John Riishede, Jörgen Lindholm, Mogens Hammer
Rok vydání: 2009
Předmět:
Zdroj: Acta Medica Scandinavica. 216:31-39
ISSN: 0001-6101
DOI: 10.1111/j.0954-6820.1984.tb03767.x
Popis: Posterior and anterior pituitary functions were assessed in 8 patients before, during, and after surgery for tumors in the suprasellar region. Preoperatively, all patients but one responded adequately to an osmotic stimulus with a rise in plasma vasopressin (AVP) and all but one showed adequate cortisol response to adrenocorticotropic hormone (ACTH) and hypoglycemia. During surgery a transient rise was seen in plasma levels of AVP (5 out of 8 patients), cortisol (7 out of 8 patients) and growth hormone (4 out of 8 patients). This response could be predicted from the preoperative stimulation tests. Postoperatively the AVP response to osmotic stimuli was impaired in 4 out of 5 patients, although urine volume had returned to normal after a transient polyuric phase. The response of plasma cortisol to ACTH was still adequate but lower than preoperatively.
Databáze: OpenAIRE