Transient, profound cataract associated with intracameral 5-fluorouracil
| Autor: | Peter E. Libre |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Antimetabolites Antineoplastic medicine.medical_specialty genetic structures Open angle glaucoma Eye disease Visual Acuity Epithelial ingrowth Cataract Ophthalmology Lens Crystalline medicine Anterior lens capsule Humans Dry needling business.industry Middle Aged medicine.disease eye diseases Surgery Fluorouracil Filtering Surgery sense organs Bleb (medicine) Complication business Glaucoma Open-Angle medicine.drug |
| Zdroj: | American Journal of Ophthalmology. 135:101-102 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/s0002-9394(02)01828-7 |
| Popis: | Purpose To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil. Design Observational case report. Methods A 51-year-old man had an encapsulated bleb after filtering surgery. The bleb was needled, and 5 mg of 5-fluorouracil was injected adjacent to the bleb. Results Within 5 minutes, vision fell to finger counting at 1 foot owing to anterior lens capsule opacification. The next day, acuity and lens clarity had returned to their preneedling status. Best-corrected acuity 7 months later was 20/15. Conclusion Entry of 5-fluorouracil into the anterior chamber after bleb needling can cause transient lens opacification. Recently, intracameral 5-fluorouracil was reported as a new treatment for epithelial ingrowth. Given the transient cataract observed in this case, the use of 5-fluorouracil for epithelial ingrowth should be considered with caution for phakic patients. |
| Databáze: | OpenAIRE |
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