Potenciais fatores de risco para o desenvolvimento de esclerose múltipla no Rio de Janeiro: um estudo caso controle
| Autor: | Luiz Claudio Santos Thuler, Hélcio Alvarenga, Kátia Regina Penha da Silva, Regina Maria Papais Alvarenga, Oscar Fernández |
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| Přispěvatelé: | [Penha da Silva, KR, Papais Alvarenga,RM] Neurology Department, Hospital da Lagoa, Federal University of the State of Rio de Janeiro(UNIRIO)Rio de Janeiro RJ,Brazil. [Penha da Silva, KR, Papais Alvarenga,RM, Alvarenga,H, Santos Thuler, LC] Postgraduate Master Program in Neurology, Federal University of the State of Rio de Janeiro(UNIRIO) Rio de Janeiro RJ,Brazil. [Fernandez y Fernandez,O] Neurology Department, Carlos Haya Teaching Hospital, Malaga, Spain. |
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Multiple Sclerosis Check Tags::Male [Medical Subject Headings] multiple sclerosis immunization tobacco Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings] fatores de risco consumption of animal brain Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] Geographicals::Geographic Locations::Americas::South America::Brazil [Medical Subject Headings] Risk Factors Surveys and Questionnaires esclerose múltipla risk factors Medicine Humans epidemiologia Factores de Riesgo Gynecology Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies [Medical Subject Headings] business.industry Potential risk Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases CNS::Multiple Sclerosis::Multiple Sclerosis Chronic Progressive [Medical Subject Headings] Brasil Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires [Medical Subject Headings] single person Tabaco Esclerosis Múltiple Check Tags::Female [Medical Subject Headings] Neurology Case-Control Studies Inmunización Female Neurology (clinical) business Brazil |
| Zdroj: | Arquivos de Neuro-Psiquiatria v.67 n.2a 2009 Arquivos de neuro-psiquiatria Academia Brasileira de Neurologia instacron:ABNEURO Arquivos de Neuro-Psiquiatria, Volume: 67, Issue: 2a, Pages: 229-234, Published: JUN 2009 |
| ISSN: | 1678-4227 |
| Popis: | PURPOSE. To evaluate potential risk factors for the development of multiple sclerosis in Brazilian patients. METHOD. A case control study was carried out in 81 patients enrolled at the Department of Neurology of the Hospital da Lagoa in Rio de Janeiro, and 81 paired controls. A standardized questionnaire on demographic, social and cultural variables, and medical and family history was used. Statistical analysis was performed using descriptive statistics and conditional logistic regression models with the SPSS for Windows software program. RESULTS. Having standard vaccinations (vaccinations specified by the Brazilian government) (OR=16.2; 95% CI=2.3-115.2), smoking (OR=7.6; 95% CI=2.1-28.2), being single (OR=4.7; 95% CI=1.4-15.6) and eating animal brain (OR=3.4; 95% CI=1.2-9.8) increased the risk of developing MS. CONCLUSIONS. RESULTS of this study may contribute towards better awareness of the epidemiological characteristics of Brazilian patients with multiple sclerosis. Yes [Port]Resumo – Objetivo: Avaliar os potenciais fatores de risco para o desenvolvimento de esclerose múltipla em pacientes brasileiros. Método: Um estudo caso-controle incluiu 81 pacientes atendidos no Departamento de Neurologia do Hospital da Lagoa, no Rio de Janeiro, e 81 controles. Um questionário padronizado incluiu variáveis demográficas, sociais e culturais, além da história familiar e clínica. A análise dos dados foi realizada por meio do programa SPSS para Windows e foi constituída de estatísticas descritivas e de um modelo de regressão logística condicional. Resultados: Pacientes com história de imunização (OR=16,2; IC95%=2,3–115,2), fumantes (OR=7,6; IC95%=2,1–28,2), solteiros (OR=4,7; IC95%=1,4–15,6) e que consumiam cérebro de animal (OR=3,4; IC95%=1,2–9,8) tiveram risco mais elevado de desenvolver esclerose múltipla quando comparados aos controles. Conclusão: Os resultados deste estudo podem contribuir para um melhor entendimento das características epidemiológicas dos pacientes brasileiros com esclerose múltipla. |
| Databáze: | OpenAIRE |
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