| Přispěvatelé: |
Karjalainen, Teemu V, Lusa, Vieda, Page, Matthew J, O'Connor, Denise, Massy-Westropp, Nicola, Peters, Susan E |
| Popis: |
Background: Carpal tunnel syndrome (CTS) is a compression neuropathy of the median nerve causing pain and numbness and tingling typically in the thumb, index and middle finger. It sometimes results in muscle wasting, diminished sensitivity and loss of dexterity. Splinting the wrist (with or without the hand) using an orthosis is usually offered to people with mild‐to‐moderate findings, but its effectiveness remains unclear. Objectives: To assess the effects (benefits and harms) of splinting for people with CTS. Search methods: On 12 December 2021, we searched the Cochrane Neuromuscular Specialised Register, CENTRAL, MEDLINE, Embase, AMED, CINAHL, ClinicalTrials.gov, and WHO ICTRP with no limitations. We checked the reference lists of included studies and relevant systematic reviews for studies. Selection criteria: Randomised trials were included if the effect of splinting could be isolated from other treatment modalities. The comparisons included splinting versus no active treatment (or placebo), splinting versus another disease‐modifying non‐surgical treatment, and comparisons of different splint‐wearing regimens. We excluded studies comparing splinting with surgery or one splint design with another. We excluded participants if they had previously undergone surgical release. Data collection and analysis: Review authors independently selected trials for inclusion, extracted data, assessed study risk of bias and the certainty in the body of evidence for primary outcomes using the GRADE approach, according to standard Cochrane methodology. Main results: We included 29 trials randomising 1937 adults with CTS. The trials ranged from 21 to 234 participants, with mean ages between 42 and 60 years. The mean duration of CTS symptoms was seven weeks to five years. Eight studies with 523 hands compared splinting with no active intervention (no treatment, sham‐kinesiology tape or sham‐laser); 20 studies compared splinting (or splinting delivered along with another non‐surgical intervention) with another non‐surgical intervention; and three studies compared different splinting regimens (e.g. night‐time only versus full time). Refereed/Peer-reviewed |
