Self-rated general health among 40-year-old Danes and its association with all-cause mortality at 10-, 20-, and 29 years' follow-up
| Autor: | Line Conradsen Hiort, Hanne Hollnagel, Volkert Siersma, Anni Brit Sternhagen Nielsen, Svend Kreiner, Thomas Drivsholm |
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| Předmět: |
Adult
Male Gerontology medicine.medical_specialty Multivariate analysis Denmark Health Status Cohort Studies Risk Factors Cause of Death Surveys and Questionnaires Outcome Assessment Health Care Epidemiology Covariate Humans Medicine Longitudinal Studies Mortality Life Style Physical Examination Aged Self-rated health business.industry Proportional hazards model Hazard ratio Public Health Environmental and Occupational Health General Medicine Middle Aged Health Surveys Self Concept Socioeconomic Factors Cohort Female business Risk assessment Follow-Up Studies Demography |
| Zdroj: | University of Copenhagen |
| Popis: | Aims: Self-rated general health (SRH) predicts future mortality. We examined all-cause mortality at 10, 20, and 29 years' follow-up and its association with SRH measured at the age of 40 years in a cohort of 1,198 healthy Danes born in 1936 and who were residents in suburban Copenhagen. Methods: The association between SRH (dichotomized into good versus poor) and all-cause mortality was estimated in standard time-homogenous Cox regression models adjusting for covariates related to mortality, and in time-heterogeneous Cox regression models without covariate adjustment, where time-heterogeneity features as a separate risk assessment for each of the three follow-up periods defined by the follow-up examinations. Results: At the age of 40 years, 153 (14.6%) of 1,045 participants reported poor and 85.4% good SRH. Dead participants totalled 36 at the 10-year, 96 at the 20-year, and 207 at the 29-year follow-up. For poor SRH, mortality hazard ratios (multivariate analysis) were persistently significant, but slowly declining with follow-up time. The time-heterogeneous models explain this feature: increased mortality risk was significant only in the first decade after assessment: 2.30 (95% CI 1.11-4.78) vs. 0.91 (95% CI 0.36-2.31) and 0.73 (95% CI 0.34-1.55). Conclusions: The association between poor SRH and mortality emphasizes the importance of health personnel taking account of people's health rating, particularly when a recent assessment has been made. SRH is related to death, even when controlling for known covariates, but it is not a long-term effect. |
| Databáze: | OpenAIRE |
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