Surfactant protein-A concentration in sera from dogs with pulmonary parenchymal diseases
| Autor: | Hideo Akiyoshi, Katsuhito Sone, Junichiro Shimizu, Yijyun Li, Shunji Sugii, Zheng Cao, Akiyoshi Hayashi, Fumihito Ohashi, Toshiyuki Tanaka |
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| Rok vydání: | 2013 |
| Předmět: |
Lung Diseases
Male Pathology medicine.medical_specialty Enzyme-Linked Immunosorbent Assay Aspiration pneumonia Dogs medicine Animals Dog Diseases Respiratory system Diffuse alveolar damage Pulmonary Surfactant-Associated Protein A Lung General Veterinary biology business.industry medicine.disease Surfactant protein A medicine.anatomical_structure Case-Control Studies biology.protein Biomarker (medicine) Female Antibody business Biomarkers |
| Zdroj: | The Journal of veterinary medical science. 75(6) |
| ISSN: | 1347-7439 |
| Popis: | Pulmonary surfactant protein A (SP-A) is used as a biomarker to understand the clinical features of pulmonary diseases and associated prognostic indices in human medicine. This study was conducted to investigate whether or not serum SP-A concentration can be used as a biomarker for identifying pulmonary parenchymal diseases in dogs. Thirty-two dogs with pulmonary parenchymal diseases, 34 with nonrespiratory diseases and 57 healthy dogs were included. Serum SP-A concentration was measured in all dogs using sandwich enzyme linked immunosorbent assay with an anti-dog SP-A polyclonal antibody. Median serum SP-A concentration in healthy dogs was |
| Databáze: | OpenAIRE |
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