Delayed sleep phase syndrome and bipolar disorder: Pathogenesis and available common biomarkers
| Autor: | Stefania Mondello, Raffaele Ferri, Firas Kobeissy, Farid Talih, Farah S. Andary, Nour Y. Gebara |
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| Rok vydání: | 2016 |
| Předmět: |
Pulmonary and Respiratory Medicine
Bipolar Disorder business.industry Delayed sleep phase Bioinformatics medicine.disease 030227 psychiatry Pathogenesis Melatonin 03 medical and health sciences 0302 clinical medicine Neurology Sleep Disorders Circadian Rhythm Circadian rhythm sleep-wake disorders Bipolar disorder Delayed sleep wake phase disorder Biomarkers Mood disorder Sleep disorders Melatonin Physiology (medical) Etiology Medicine Humans Neurology (clinical) Circadian rhythm Bipolar disorder business 030217 neurology & neurosurgery Biomarkers medicine.drug |
| Zdroj: | Sleep medicine reviews. 41 |
| ISSN: | 1532-2955 |
| Popis: | Circadian rhythm disturbances are common in bipolar affective disorder (BD). Delayed sleep-wake phase syndrome (DSWPD) is the most prevalent circadian rhythm sleep-wake disorder (CRSWDs) and is frequently observed in BD. It is unclear whether DSWPD in BD is an independent process or is a consequence of BD. In this hypothetical review, we discuss the overlap between BD and DSWPD and potential common biomarkers for DSWPD and BD. The review will include a discussion of the genetics of DSWPD and BD. Biomarkers elucidating the pathophysiological processes occurring in these two disorders may offer insight into the etiology and prognosis of both conditions. |
| Databáze: | OpenAIRE |
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