Language monitoring in multilingual patients undergoing awake craniotomy: a case study of a German-English-French trilingual patient with a WHO grade II glioma
| Autor: | Jean-François Démonet, Vincent Lubrano, Barbara Köpke, Katia Prod'Homme |
|---|---|
| Přispěvatelé: | Imagerie cérébrale et handicaps neurologiques (ICHN), Institut des sciences du cerveau de Toulouse. (ISCT), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Octogone Unité de Recherche Interdisciplinaire (Octogone), Université Toulouse - Jean Jaurès (UT2J), Centre Leenaards de la Mémoire, Université de Lausanne (UNIL)-CHUV |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Linguistics and Language
medicine.medical_specialty Bilingualism Cognitive Neuroscience First language Experimental and Cognitive Psychology Audiology Brain mapping 050105 experimental psychology Developmental psychology German 03 medical and health sciences 0302 clinical medicine Arts and Humanities (miscellaneous) Broca's area Multilingual medicine 0501 psychology and cognitive sciences Neuroscience of multilingualism Language switching WHO Grade II Glioma 05 social sciences Bilingual aphasia test Inferior frontal cortex [SCCO.LING]Cognitive science/Linguistics language.human_language Awake craniotomy language Psychology 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neurolinguistics Journal of Neurolinguistics, Elsevier, 2012, 25, pp.567-578. ⟨10.1016/j.jneuroling.2011.08.002⟩ |
| ISSN: | 0911-6044 |
| DOI: | 10.1016/j.jneuroling.2011.08.002⟩ |
| Popis: | International audience; In this paper, we report a case study of a 31-year-old multilingual female (LK) who presented with a left prefrontal brain tumour (WHO grade II glioma). LK is a late trilingual person whose first language is German. She had been learning English and French for 10 years when she moved to France at the age of 20 and now mostly uses French. German (L1) and French (L3) were assessed using a selection of sub-tests taken from the MT 86, the French version of the BDAE, the ECOSSE, the MEC, the German BAT, and, a non-standardized German adaptation of parts of the MEC. Preoperatively, LK had no language deficit. She was operated on under awake craniotomy, and both languages were mapped. Direct intraoperative electrical stimulation mapping showed that i) L1 and L3 were represented by both distinct and overlapping areas within the left (dominant) inferior frontal cortex, but shared the same subcortical tracts, and ii) the left dorsolateral prefrontal cortex was engaged when switching from one language to another. Since surgery, the patient has been followed longitudinally, with six-monthly assessments of her language skills using the same test battery. Her L1 and L3 language skills have been intact for 24 months postoperatively. After presenting the behavioural and brain mapping data, we discuss their relevance with respect to the organization of language skills within the frontal cortex and deep frontal structures. |
| Databáze: | OpenAIRE |
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