Participation of cholinergic systems in the bulbar mechanisms of the regulation of breathing
Autor: | V E Kuz'mina, L I Sergeeva |
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Rok vydání: | 1994 |
Předmět: |
Intercostal Muscles
Muscarinic Antagonists Nicotinic Antagonists Biology Parasympathetic nervous system Parasympathetic Nervous System medicine Animals Respiratory system Medulla Oblongata Electromyography General Neuroscience Respiratory center Anatomy Spinal cord Acetylcholine Rats Electrophysiology medicine.anatomical_structure Spinal Cord Respiratory Mechanics Breathing Medulla oblongata Cholinergic Neuroscience medicine.drug |
Zdroj: | Neuroscience and Behavioral Physiology. 24:475-478 |
ISSN: | 1573-899X 0097-0549 |
DOI: | 10.1007/bf02360169 |
Popis: | The reactions of the respiratory muscles of symmetrical intercostals given bi- and unilateral applications of acetylcholine and its antagonists (atropine and spasmolytin) to various segments of the dorsal surface of the medulla oblongata, the entire region of the projection of the respiratory center, primarily its medial or primarily its lateral zones, were studied in rats. A relationship of the effect to the level of activity of cholinergic structures and the localization of the exposure, was identified. The results obtained suggest an uneven distribution of the M and N cholinoreactive systems in homotopic structures of the medulla oblongata. A conclusion was drawn of the undoubted participation of cholinergic mediation in the mechanisms of integration of paired divisions of the bulbar respiratory center and the central regulation of respiration. |
Databáze: | OpenAIRE |
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