Serum and Salivary IgA Levels in Normal Subjects: Comparison between Tonsillectomized and Non-Tonsillectomized Subjects

Autor: L. Palmisano, Raffaele D'Amelio, Fernando Aiuti, S. Le Moli, R. Seminara
Rok vydání: 1982
Předmět:
Zdroj: International Archives of Allergy and Immunology. 68:256-259
ISSN: 1423-0097
1018-2438
DOI: 10.1159/000233108
Popis: Serum IgA and secretory IgA (SIgA) were determined in 1,000 apparently healthy subjects; 274 were tonsillectomized. Four groups were identified in this study: (1) 0.3% of subjects had no serum IgA and SIgA; (2) 1.6% of subjects showed partial serum and SIgA deficiency; (3) 27.4% of individuals were tonsillectomized and had partial serum IgA deficiency but normal SIgA, and (4) 71.4% were normal, both with respect to serum IgA and SIgA. These results stress the relatively high incidence of IgA deficiency in the normal population and confirm the role of the tonsils in maintaining serum IgA levels.
Databáze: OpenAIRE