The 2021 WHO classification of tumors of the central nervous system: A summary
| Autor: | Andreas von Deimling, Arie Perry, Ho Keung Ng, David N. Louis, David W. Ellison, Dominique Figarella-Branger, Guido Reifenberger, Riccardo Soffietti, Cynthia Hawkins, Pieter Wesseling, Daniel J. Brat, Stefan M. Pfister, Ian A. Cree |
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| Přispěvatelé: | Pathology, CCA - Imaging and biomarkers, Institut de neurophysiopathologie (INP), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Service d'Anatomie Pathologique et de Neuropathologie [Hôpital de la Timone - CHU - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Central Nervous System
Cancer Research diagnosis WHO Classification Summary [SDV]Life Sciences [q-bio] MESH: World Health Organization MESH: Central Nervous System Neoplasms Central Nervous System Neoplasms 0302 clinical medicine Pathology Medicine Pathology Molecular Cancer 0303 health sciences Brain 3. Good health medicine.anatomical_structure Oncology classification 030220 oncology & carcinogenesis brain tumor Central nervous system Oncology and Carcinogenesis Brain tumor World Health Organization central nervous system Humans brian tumor 03 medical and health sciences MESH: Brain Rare Diseases Taxonomy (general) MESH: Central Nervous System CNS TUMORS Oncology & Carcinogenesis Letters to the Editor Grading (tumors) 030304 developmental biology MESH: Pathology Molecular MESH: Humans business.industry Neurosciences Molecular medicine.disease Brain Disorders Brain Cancer Neurology (clinical) Who classification business Neuroscience |
| Zdroj: | Neuro-Oncology, 23(8), 1231-1251. Oxford University Press Neuro-Oncology Neuro-Oncology, Oxford University Press (OUP), 2021, 23 (8), pp.1231-1251. ⟨10.1093/neuonc/noab106⟩ Louis, D N, Perry, A, Wesseling, P, Brat, D J, Cree, I A, Figarella-Branger, D, Hawkins, C, Ng, H K, Pfister, S M, Reifenberger, G, Soffietti, R, von Deimling, A & Ellison, D W 2021, ' The 2021 WHO classification of tumors of the central nervous system: A summary ', Neuro-Oncology, vol. 23, no. 8, pp. 1231-1251 . https://doi.org/10.1093/neuonc/noab106 Neuro Oncol Neuro-oncology, vol 23, iss 8 Neuro-Oncology, 2021, 23 (8), pp.1231-1251. ⟨10.1093/neuonc/noab106⟩ |
| ISSN: | 1522-8517 1523-5866 |
| DOI: | 10.1093/neuonc/noab106⟩ |
| Popis: | The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors. Building on the 2016 updated fourth edition and the work of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy, the 2021 fifth edition introduces major changes that advance the role of molecular diagnostics in CNS tumor classification. At the same time, it remains wedded to other established approaches to tumor diagnosis such as histology and immunohistochemistry. In doing so, the fifth edition establishes some different approaches to both CNS tumor nomenclature and grading and it emphasizes the importance of integrated diagnoses and layered reports. New tumor types and subtypes are introduced, some based on novel diagnostic technologies such as DNA methylome profiling. The present review summarizes the major general changes in the 2021 fifth edition classification and the specific changes in each taxonomic category. It is hoped that this summary provides an overview to facilitate more in-depth exploration of the entire fifth edition of the WHO Classification of Tumors of the Central Nervous System. |
| Databáze: | OpenAIRE |
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